盛心磊课题组将立足于蛋白质翻译后修饰（PTMs）和先天免疫调控研究，发挥其在蛋白质组学技术开发方面的优势，深入研究在病毒感染过程中和免疫细胞内翻译后修饰的功能和调控机制，深化“生物医学+人工智能”交叉研究，推动蛋白质组学驱动的精准医疗创新。

* Equal contributions

1. Sheng, X., Lin, H., Cole, C.A., Zhao, Y. (2025). Biochemistry and regulation of histone lysine L-lactylation. Nature Reviews Molecular Cell Biology.

2. Gao, Y., Sheng, X.*, Tan, D., Kim, S., Choi, S., Paudel, S., Lee, T., Yan, C., Tan, M., Kim, K.M., Cho, S.S., Ki, S.H., Huang, H., Zhao, Y., Lee, S. (2023). Identification of Histone Lysine Acetoacetylation as a Dynamic Post-Translational Modification Regulated by HB01. Advanced Science.

3. Song, B., Sheng, X.*, Justice, J.L., Lum, K.K., Metzger, P.J., Cook, K.C., Kostas, J.C., Cristea, I.M. (2023). Intercellular communication within the virus microenvironment affects the susceptibility of cells to secondary viral infections. Science Advances.

4. Shi, W., Sheng, X.*, Dorr, K.M., Hutton, J.E., Emerson, J.I., Davies, H.A., Andrade, T.D., Wasson, L.K., Greco, T.M., Hashimoto, Y., Federspiel, J.D., Robbe, Z.L., Chen, X., Arnold, A.P., Cristea, I.M., Conlon, F.L. (2021). Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation. Developmental Cell.

5. Sheng, X., Cristea, I.M. (2021). The antiviral sirtuin 3 bridges protein acetylation to mitochondrial integrity and metabolism during human cytomegalovirus infection. PLoS Pathogens.