课题组运用单细胞RNA测序，遗传学，影像学，电生理，细胞和分子生物学以及动物行为学等多种技术，研究1) 记忆存储的细胞和分子机理, 包括神经元和神经元胶质细胞的作用机制；2）神经元突触形成的胞内信号转导机制。

近期代表性论:

Jiang X, Sando R, and Südhof TC. Multiple signaling pathways are essential for synapse formation induced by synaptic adhesion molecules. Proc Natl Acad Sci USA. January 19, 2021 118 (3) e2000173118; doi.org/10.1073/pnas.2000173118.

Chen MB*, Jiang X*, Quake SR#, and Südhof TC#. Persistent transcriptional programs are associated with remote memory. Nature, 2020, 587:437-442. *these authors contribute equally #co-corresponding author. doi:10.1038/s41586-020-2905-5.

Sando R, Jiang X, and Südhof TC. Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins. Science 2019, 363(6429). doi:10.1126/science.aav7969

Jiang X, Li L, Ying Z, Pan C, Huang S, Li L, Dai M, Yan B, Li M, Jiang H, Chen S, Zhang Z, and Wang X. A Small Molecule That Protects the Integrity of the Electron Transfer Chain Blocks the Mitochondrial Apoptotic Pathway. Mol Cell 2016, 63: 229-239. (Cover Story) doi:10.1016/j.molcel.2016.06.016

Jiang X, Jiang H, Shen Z, and Wang X. Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis. Proc Natl Acad Sci USA. 2014, 111(41):14782-7. doi:10.1073/pnas.1417253111