课题组位于生物学、医学、化学和材料科学等多学科交叉的前沿领域，融合前沿科技和创新思维，致力于挑战和解决生物医药领域中的关键科学难题。课题组聚焦于功能性多肽的设计与构建，结合化学生物学、分子生物学等领域的先进技术和理论，探索功能性多肽在分子识别、细胞机制研究以及核酸药物递送等关键性领域的广泛应用，开发新型的、具有临床应用潜力的创新药物及生物材料等。

M. Li, R. Puschmann, A, Herdlitschka, D. Fiedler, H. Wennemers; Delivery of myo-inositol hexakisphosphate to the cell nucleus with a proline-based cell penetrating peptide; Angew. Chem. Int. Ed. 2020, 59, 15586 (hot paper).

M. Li, M. R. Stojković, M. Ehlers, E. Zellermann, I. Piantanida, C. Schmuck; Use of an Octapeptide–Guanidiniocarbonylpyrrole Conjugate for the Formation of a Supramolecular β‐Helix that Self‐Assembles into pH‐Responsive Fibers; Angew. Chem. Int. Ed. 2016, 55, 13015.

M. Li, M. Ehlers, S. Schlesiger, E. Zellermann, S. K. Knauer, C. Schmuck; Incorporation of a Non‐Natural Arginine Analogue into a Cyclic Peptide Leads to Formation of Positively Charged Nanofibers Capable of Gene Transfection; Angew. Chem. Int. Ed. 2016, 55, 598.

M. Li, S. Schlesiger, S. K. Knauer, C. Schmuck; A Tailor‐Made Specific Anion‐Binding Motif in the Side Chain Transforms a Tetrapeptide into an Efficient Vector for Gene Delivery; Angew. Chem. Int. Ed. 2015, 54, 2984.

M. Li, S. Schlesiger, S. K. Knauer, C. Schmuck; A dipeptide with enhanced anion binding affinity enables cell uptake and protein delivery; Org. Biomol. Chem. 2018, 16, 2312.