唐啸宇课题组结合化学、基因组学、合成生物学手段探究微生物相关代谢产物介导的“微生物-微生物”和“微生物-宿主” 互作，从基因和化学分子水平解析并调控生命的互作活动，为活菌药物、微生物组药物、和“新一代”小分子药物的开发奠定基础。

H. Zhang, X. Li, S. Huang, M. Cai, W. Shi, M. Liang, Y. Lin, J. Shen, M. Sui, Q. Lai, J. Dou, Z. Shao, X. Luo, Y. Ge*, X. Tang*. A semisynthesis platform for efficient production and exploration of didemnin-based drugs. Angew. Chem. Int. Ed., 2024, e202318784

H. Zou, Z. Hui, R.A. Shepherd, S. Zhao, Y. Wu, Z. Shen, C. Pang, S. Zhou, Z. Yu, J. Zhou, B.S. Moore, L.M. Sanchez, X. Tang*. Unveiling a CAAX protease-like protein involved in didemnin drug maturation and secretion. Advanced Science, 2024, 11(4), e2306044

Y. Zhang, G. Liao, M. Wang, Z. Zhang, L. Liu, Y. Song, D. Wang, T. Hao, J. Feng, B. Xia, Y. Wang, X. Tang*, Y. Chen*. Human-associated bacteria adopt an unusual route for synthesizing 3-acetylated tetramates for environmental adaptation. Microbiome, 2023, 11, 97

L. Hou, H. Tian, L. Wang, Z. E. Ferris, J. Wang, M. Cai, E. A. Older, M. R. K. Raja, D. Xue, W. Sun, P. Nagarkatti, M. Nagarkatti, H. Chen, D. Fan, X. Tang*, J. Li*. Identification and biosynthesis of pro-inflammatory sulfonolipids from an opportunistic pathogen Chryseobacterium gleum. ACS Chemical Biology 2022, 17(5), 1197–1206

H. Zhang, G. Liao, X. Luo*, X. Tang*. Harnessing nature’s biosynthetic capacity to facilitate total synthesis. National Science Review 2022, 9(10), nwac178