The Amunts Lab studies the structural basis of cellular energy conversion, with a particular focus on how mitochondrial bioenergetic membrane protein complexes are assembled, organized, and regulated in their native context. The group combines cryo-electron microscopy, cryo-electron tomography, biochemistry, and computational analysis to investigate the molecular mechanisms of bioenergetic machineries across functional states. Current research places strong emphasis on mitochondrial cristae organization, respiratory complexes and supercomplexes, and the relationship between membrane architecture and function in health, aging, and disease.
The lab has a strong track record in the structural analysis of large macromolecular assemblies, including mitoribosomes, chlororibosomes, photosystems, and ATP synthase. At SMART, the group is expanding its research program in native and in-situ structural biology of bioenergetic membranes.
1. Postdoctoral Fellow
Job Responsibilities:
(1)Conduct independent and collaborative research ;
(2)Develop and optimize workflows for structural studies of membrane protein complexes ;
(3)Perform cryo-EM sample preparation, data processing, and structure analysis ;
(4)Assist in mentoring junior lab members and fostering a collaborative research environment .
Qualifications:
(1)Ph.D. in structural biology, biochemistry, biophysics, cell biology, or a related field ;
(2)Strong research background macromolecular complexes, membrane proteins, or related areas ;
(3)Demonstrated ability to conduct independent research and publish scientific work ;
(4)Strong sense of academic integrity, scientific rigor, and teamwork .
What We Offer:
The position offers the opportunity to join a dynamic and international research environment at SMART and to contribute to a growing program in structural biology and bioenergetics. The successful candidate will have access to advanced research infrastructure, strong scientific mentorship, and significant opportunities for professional development.
Applicants should provide:
(1)Cover letter
(2)Curriculum vitae
(3)List of publications or preprints
(4)Contact information for referees
Please send applications and informal inquiries to Alexey Amunts amunts@smart.org.cn
All applications will be kept confidential, and compensation is negotiable.
This recruitment notice remains open until all positions are filled.