Dr. Bing Zhang's research focuses on interdisciplinary studies in neurology, immunology, and tissue regeneration. The lab investigates how neural signals regulate stem cell activation and the remodeling of immune microenvironments. Additionally, the team explores the mechanisms underlying cellular interaction imbalances in skin and hair disorders. Moreover, the team develops innovative therapies for skin diseases and regenerative disorders by integrating human multi-omics data with in vitro models, advancing precision treatment in regenerative medicine.

Dr. Bing Zhang’s previous work revealed the coordinated growth mechanisms of various skin cells during hair follicle regeneration (Gene Dev, 2016) and demonstrated that the sympathetic nervous system can directly regulate stem cell activity (Nature, 2020), confirming the essential role of neuro-stem cell interactions in brain-body communications. Recently, his team uncovered the mechanisms of interaction between the hypothalamus-pituitary-adrenal (HPA) axis and the stem cell microenvironment (Cell, 2025), elucidating the close relationship between systemic physiological changes and tissue regeneration.

2015-2020，Postdoctoral Fellow, Harvard University

2007-2015，Ph.D.in Biochemistry, Case Western Reserve University

2003-2007，Bachelor of Science, Shandong University

2020-present，Principal Investigator，School of Life Sciences, Westlake University

Harvard University Distinguished Teaching Award

Charles A. King Trust Postdoctoral Fellowship

1. Han Chen*, Chao Liu*, Shiyao Cui*, Yingqian Xia, Ke Zhang, Hanxiao Cheng, Jingyu Peng, Xiaoling Yu, Luyang Li, Hualin Yu, Jufang Zhang, Ju-Sheng Zheng and Bing Zhang (2025)Intermittent fasting triggers interorgan communication to suppress hair follicle regeneration. Cell, doi.org/10.1016/j.cell.2024.11.004.

2. Bing Zhang^#and Ting Chen^#(2023)Local and systemic mechanisms that control the hair follicle stem cell niche.Nature Reviews Molecular Cell Biology(^#Co-corresponding author), doi.org/10.1038/s41580-023-00662-3.

3. Jingyu Peng, Han Chen, Bing Zhang (2022)Nerve-stem cell crosstalk in skin regeneration and diseases.Trends in Molecular Medicine,doi.org/10.1016/j.molmed.2022.04.005.

4. Bing Zhang, Sai Ma, Inbal Rachmin, Megan He, Pankaj Baral, Sekyu Choi, William A. Gonçalves, Yulia Shwartz, Eva M. Fast, Yiqun Su, Leonard I. Zon, Aviv Regev, Jason D. Buenrostro, Thiago M. Cunha, Isaac M. Chiu, David E. Fisher and Ya-Chieh Hsu (2020) Hyperactivation of Sympathetic Nerves Drives Melanocyte Stem Cell Depletion. Nature, doi.org/10.1038/s41586-020-1935-3.

5. Bing Zhang*, Pai-Chi Tsai*, Meryem Gonzalez-Celeiro, Oliver Chung, Benjamin Boumard, Carolina N. Perdigoto, Elena Ezhkova and Ya-Chieh Hsu (2016) Hair Follicles’ Transit Amplifying Cells Govern Concurrent Dermal Adipocyte Production through Sonic Hedgehog. Genes and Development (*Co-first author), doi.org/10.1101/gad.285429.116.

We currently have several openings for graduate students, research assistants & postdocs. Please submit your CV or resume through email if interested.